Myocardial Ischemia End-Diastolic Wall Thickness as a Predictor of Recovery of Function in Myocardial Hibernation Relation to Rest-Redistribution Tl-201 Tomography and Dobutamine Stress Echocardiography

RESULTS Global wall motion score index decreased from 2.38 6 0.73 to 1.94 6 0.82 after revascularization (p , 0.001). Thirty-eight percent of severely dysfunctional segments recovered resting function. Compared to segments without recovery of resting function, those with recovery had greater EDWT (0.94 6 0.18 cm vs. 0.67 6 0.22 cm, p # 0.0001) and a higher Tl-201 uptake (78 6 13% vs. 59 6 21%; p , 0.0001). An EDWT .0.6 cm had a sensitivity of 94% and specificity of 48% for recovery of function. Similarly, a Tl-201 maximal uptake of $60% had a sensitivity of 91% and specificity of 50%. Receiver operating characteristic curves for prediction of recovery of regional and global function were similar for EDWT and maximum Tl-201 uptake. Combination of EDWT and any contractile reserve during DSE for recovery of regional function improved the specificity to 77% without a significant loss in sensitivity (88%).